Cyber-Physical Systems (CPS) are engineered systems that require tight interaction between physical and computational components. Designing a CPS is highly challenging because these systems are inherently complex, need significant effort to describe and evaluate a vast set of cross-disciplinary interactions, and require seamless meshing of physical elements with corresponding software artifacts. Moreover, a large set of architectural and compositional alternatives must be systematically explored and evaluated in the context of a highly constrained design space.